MOTS-C vs SS-31 (Elamipretide) vs Humanin

Mechanism, receptor target, half-life, dose, and best-price vendor side by side.

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FieldMOTS-CSS-31 (Elamipretide)Humanin
Receptor targetAMPK activation (mitochondrial-derived peptide)Cardiolipin (inner mitochondrial membrane)FPR2 / FPRL-1 / CNTFR (apoptosis inhibition)
Mechanism classmitochondrialmitochondrialmitochondrial
Half-life~1 hour (circulating); longer intracellular effects~2 hours~1 hour
Typical dose5–10 mg weekly SC1–5 mg daily SC5–10 mg weekly SC (research)
Sequence length16 residues4 residues24 residues
Best-price vendor
Glacier Aminos →
$47.99 (20mg) — $2.40/mg
Glacier Aminos →
$27.59 (10mg) — $2.76/mg
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Pricing pulls live from our vendor database. Molecular data comes from published peptide literature. For full dosing protocols, side effects, and research citations, open each peptide's individual page.