SS-31 (Elamipretide) vs MOTS-C vs Humanin

Mechanism, receptor target, half-life, dose, and best-price vendor side by side.

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FieldSS-31 (Elamipretide)MOTS-CHumanin
Receptor targetCardiolipin (inner mitochondrial membrane)AMPK activation (mitochondrial-derived peptide)FPR2 / FPRL-1 / CNTFR (apoptosis inhibition)
Mechanism classmitochondrialmitochondrialmitochondrial
Half-life~2 hours~1 hour (circulating); longer intracellular effects~1 hour
Typical dose1–5 mg daily SC5–10 mg weekly SC5–10 mg weekly SC (research)
Sequence length4 residues16 residues24 residues
Best-price vendor
Ion Peptide →
$139.00 (50mg) — $2.78/mg
Ion Peptide →
$115.00 (40mg) — $2.88/mg
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Pricing pulls live from our vendor database. Molecular data comes from published peptide literature. For full dosing protocols, side effects, and research citations, open each peptide's individual page.