Disclosure: We earn a commission from vendors on this page. Rankings are based on price, COA availability, and reputation.

Best GLP-1 Peptides (2026)

GLP-1 receptor agonists are the most effective peptide class for appetite control and metabolic health. We ranked vendors for every GLP-1 peptide by price, COA testing, and reputation.

At a Glance

1
Retatrutide3 vendors

Triple agonist (GLP-1/GIP/glucagon) with the highest weight loss in trials — up to 24% body weight. Side effects comparable to other GLP-1s.

Triple agonist (GLP-1/GIP/glucagon) with the highest weight loss in trials — up to 24% body weight. Side effects comparable to other GLP-1s.

VendorPriceAmount$/mgCOA
EZ Peptides$80.0012mg$6.67/mgYesBuy →
EZ Peptides$265.0048mg$5.52/mgYesBuy →
Penguin Peptides$72.0010mg$7.20/mgYesBuy →
See all Retatrutide vendors →
2
Tirzepatide3 vendors

Dual GLP-1/GIP agonist. Up to 22.5% weight loss in SURMOUNT trials. FDA-approved with strong safety data.

Dual GLP-1/GIP agonist. Up to 22.5% weight loss in SURMOUNT trials. FDA-approved with strong safety data.

VendorPriceAmount$/mgCOA
EZ Peptides$55.0010mg$5.50/mgYesBuy →
EZ Peptides$80.0015mg$5.33/mgYesBuy →
EZ Peptides$85.0020mg$4.25/mgYesBuy →
See all Tirzepatide vendors →
3
Semaglutide3 vendors

Gold standard single GLP-1 agonist. ~15% weight loss. Most clinical data of any peptide in this class.

Gold standard single GLP-1 agonist. ~15% weight loss. Most clinical data of any peptide in this class.

VendorPriceAmount$/mgCOA
EZ Peptides$40.005mg$8.00/mgYesBuy →
EZ Peptides$60.0010mg$6.00/mgYesBuy →
Penguin Peptides$59.005mg$11.80/mgYesBuy →
See all Semaglutide vendors →
4
Cagrilintide1 vendor

Amylin analog that pairs with semaglutide. Promising combo data but limited as a standalone.

Amylin analog that pairs with semaglutide. Promising combo data but limited as a standalone.

VendorPriceAmount$/mgCOA
Certified Pep$128.0010mg$12.80/mgYesBuy →
See all Cagrilintide vendors →
5

First-gen daily GLP-1. ~8% weight loss. Largely superseded by weekly options but well-studied.

First-gen daily GLP-1. ~8% weight loss. Largely superseded by weekly options but well-studied.

No vendors currently in stock.

How We Rank Vendors

Every vendor is scored on three factors: price per mg (40%), third-party COA testing (30%), and community reputation (30%). Scores floor at 8.0 — if a vendor is on our site, they are worth buying from.

Price (40%)

Normalized to $/mg for fair comparison across vial sizes.

COA Testing (30%)

Third-party lab results confirming purity and identity.

Reputation (30%)

Community feedback, shipping reliability, and track record.

Peptides A–Z

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