Disclosure: We earn a commission from vendors on this page. Rankings are based on price, COA availability, and reputation.
Best GLP-1 Peptides (2026)
GLP-1 receptor agonists are the most effective peptide class for appetite control and metabolic health. We ranked vendors for every GLP-1 peptide by price, COA testing, and reputation.
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At a Glance
1Retatrutide3 vendorsTriple agonist (GLP-1/GIP/glucagon) with the highest weight loss in trials — up to 24% body weight. Side effects comparable to other GLP-1s.
Triple agonist (GLP-1/GIP/glucagon) with the highest weight loss in trials — up to 24% body weight. Side effects comparable to other GLP-1s.
Triple agonist (GLP-1/GIP/glucagon) with the highest weight loss in trials — up to 24% body weight. Side effects comparable to other GLP-1s.
| Vendor | Price | Amount | $/mg | COA | |
|---|---|---|---|---|---|
| Nura Peptide | $205.00 | 50mg | $4.10/mg | Yes | Buy → |
| Ascension Peptides | $250.00 | 30mg | $8.33/mg | Yes | Buy → |
| Ion Peptide | $219.00 | 60mg | $3.65/mg | Yes | Buy → |
2Tirzepatide3 vendorsDual GLP-1/GIP agonist. Up to 22.5% weight loss in SURMOUNT trials. FDA-approved with strong safety data.
Dual GLP-1/GIP agonist. Up to 22.5% weight loss in SURMOUNT trials. FDA-approved with strong safety data.
Dual GLP-1/GIP agonist. Up to 22.5% weight loss in SURMOUNT trials. FDA-approved with strong safety data.
| Vendor | Price | Amount | $/mg | COA | |
|---|---|---|---|---|---|
| Nura Peptide | $155.00 | 60mg | $2.58/mg | Yes | Buy → |
| Ascension Peptides | $180.00 | 30mg | $6.00/mg | Yes | Buy → |
| Ion Peptide | $199.00 | 100mg | $1.99/mg | Yes | Buy → |
3Semaglutide3 vendorsGold standard single GLP-1 agonist. ~15% weight loss. Most clinical data of any peptide in this class.
Gold standard single GLP-1 agonist. ~15% weight loss. Most clinical data of any peptide in this class.
Gold standard single GLP-1 agonist. ~15% weight loss. Most clinical data of any peptide in this class.
| Vendor | Price | Amount | $/mg | COA | |
|---|---|---|---|---|---|
| Nura Peptide | $55.00 | 10mg | $5.50/mg | Yes | Buy → |
| Ascension Peptides | $38.00 | 5mg | $7.60/mg | Yes | Buy → |
| Ion Peptide | $69.00 | 20mg | $3.45/mg | Yes | Buy → |
4Cagrilintide3 vendorsAmylin analog that pairs with semaglutide. Promising combo data but limited as a standalone.
Amylin analog that pairs with semaglutide. Promising combo data but limited as a standalone.
Amylin analog that pairs with semaglutide. Promising combo data but limited as a standalone.
| Vendor | Price | Amount | $/mg | COA | |
|---|---|---|---|---|---|
| Nura Peptide | $99.00 | 10mg | $9.90/mg | Yes | Buy → |
| Ascension Peptides | $100.00 | 10mg | $10.00/mg | Yes | Buy → |
| Ion Peptide | $99.00 | 10mg | $9.90/mg | Yes | Buy → |
5First-gen daily GLP-1. ~8% weight loss. Largely superseded by weekly options but well-studied.
First-gen daily GLP-1. ~8% weight loss. Largely superseded by weekly options but well-studied.
First-gen daily GLP-1. ~8% weight loss. Largely superseded by weekly options but well-studied.
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How We Rank Vendors
Every vendor is scored on three factors: price per mg (40%), third-party COA testing (30%), and community reputation (30%). Scores floor at 8.0 — if a vendor is on our site, they are worth buying from.
Normalized to $/mg for fair comparison across vial sizes.
Third-party lab results confirming purity and identity.
Community feedback, shipping reliability, and track record.