Trials6 min read
Retatrutide Hits 30.3% Weight Loss in TRIUMPH-1
TRIUMPH-1 Phase 3 data drops: 30.3% body weight loss at 104 weeks, 2,339 patients. What the numbers mean for the NDA and buyers.
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Trials9 min read
MBX 4291: Monthly GLP-1 Hits 7% Weight Loss in Phase 1
MBX Biosciences' monthly GLP-1/GIP injection lost 7% at 8 weeks Phase 1 with no nausea. PK supports true monthly dosing. What buyers should know.
Trials8 min read
Retatrutide TRIUMPH-1: Q2 Readout Anchors NDA
Lilly's TRIUMPH-1 obesity readout drops Q2 2026 — the 80-week data that anchors retatrutide's NDA. What to expect, dose, and where to source.
Trials7 min read
Survodutide Phase 3: 16.6% Weight Loss in SYNCHRONIZE-1
Boehringer's GLP-1/glucagon dual agonist hit 16.6% weight loss at 76 weeks — comparable to semaglutide, short of tirzepatide. What it means for buyers.
Trials6 min read
Eloralintide: Lilly Amylin Drug Hits 20% Weight Loss
Lilly's eloralintide hit 20% weight loss at 48 weeks in Phase 2 — without GLP-1. Here's what the amylin-only data means for obesity drugs.
Trials9 min read
Pfizer's Monthly GLP-1 Shot PF-3944: Phase 2b Results
Pfizer's once-monthly GLP-1 shot PF-3944 hit 12.3% placebo-adjusted weight loss in phase 2b. 10 phase 3 trials launching. Here is what it means.
Trials6 min read
Semaglutide Cuts Heart Risk 29% More Than Tirzepatide
New STEER study: semaglutide cut major cardiac events 29% more than tirzepatide in obesity patients without diabetes. What it means for stack choice.
Trials7 min read
Semaglutide Reverses Knee Cartilage: New Study
May 2026 research: semaglutide reverses knee cartilage damage independent of weight loss. MRI showed 17% thicker cartilage. What it means.
Trials6 min read
Retatrutide Tingling: 20.9% Hit by Dysesthesia
TRIUMPH-4 Phase 3 found 1 in 5 patients on retatrutide 12mg develop dysesthesia. What it feels like, why it happens, and how to manage it without quitting.
Trials8 min read
GLP-1 for Alzheimer's: 2026 Trial Results (Mixed)
Semaglutide EVOKE trial missed its primary endpoint. Liraglutide ELAD showed 50% less brain volume loss. What the 2026 data means for GLP-1 peptide buyers.
Trials12 min read
Retatrutide Phase 3: 28.7% Weight Loss
TRIUMPH-4 showed 28.7% weight loss at 68 weeks — surpassing every competitor. Phase 3 results, safety data, and timeline.