Hormone Analogs
Synthetic analogs of endogenous hormones — oxytocin, kisspeptin, VIP — that recapitulate native signaling for targeted effects on bonding, reproduction, and gut motility.
4 peptides in this class
Gonadorelin
→Target: GnRH receptor (GnRHR) — pituitary gonadotrophs
Synthetic GnRH decapeptide that signals the pituitary to release LH and FSH.
Kisspeptin
→Target: Kiss1R (GPR54) — HPG axis
Kisspeptin is a neuropeptide that acts as the master regulator of the reproductive hormone axis. It stimulates GnRH release from the hypothalamus, which triggers LH and FSH secretion. Used in fertility treatments, hormone optimization, and research into puberty and reproductive disorders. Also shows promise for metabolic regulation and mood.
Oxytocin
→Target: Oxytocin receptor (OXTR)
Oxytocin is a 9-amino acid neuropeptide known as the 'love hormone' or 'bonding hormone.' Produced in the hypothalamus and released by the pituitary gland, it plays crucial roles in social bonding, trust, empathy, sexual reproduction, childbirth, and breastfeeding. Research explores its potential for anxiety, autism spectrum disorders, and relationship enhancement.
VIP
→Target: VPAC1 / VPAC2 receptors
VIP (Vasoactive Intestinal Peptide) is a 28-amino-acid neuropeptide with broad immunomodulatory, neuroprotective, and vasodilatory effects. Central to the Shoemaker protocol for CIRS/mold illness treatment. Also researched for pulmonary hypertension, circadian rhythm regulation, and neuroinflammation.
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