Tissue Repair & Angiogenic Peptides

Peptides that accelerate wound healing through angiogenesis, fibroblast recruitment, and growth-factor signaling. Most act through VEGF or FGF pathways and modulate endothelial migration.

4 peptides in this class

BPC-157

Target: VEGFR2 / eNOS pathway

BPC-157 (Body Protection Compound-157) is a synthetic peptide derived from a protein found in gastric juice. Studied extensively for tissue repair, wound healing, and anti-inflammatory effects. Popular in research for tendon, ligament, muscle, and gut healing applications.

Half-life: ~4 hours (oral form may have longer effective window)Dose: 250–500 mcg daily SC

GHK-Cu

Target: Copper-peptide complex (gene expression, fibroblast activation)

GHK-Cu (Copper Peptide) is a naturally occurring tripeptide with a copper ion that declines with age. Researched for wound healing, skin regeneration, anti-aging, hair growth, and collagen synthesis. Available in topical and injectable forms for research.

Half-life: ~30 minutesDose: 1–2 mg daily SC or topical

TB-500

Target: Actin-sequestering (thymosin beta-4 fragment)

TB-500 (Thymosin Beta-4 fragment) is a synthetic peptide that promotes tissue repair, cell migration, and angiogenesis. Researched for wound healing, flexibility, injury recovery, and reducing inflammation. Often discussed alongside BPC-157 for synergistic healing effects.

Half-life: ~2–3 hoursDose: 2–2.5 mg 2x weekly SC (loading), then weekly

Thymosin Beta-4

Target: Actin-sequestering / ILK pathway

Thymosin Beta-4 (TB-4) is the full-length 43 amino acid peptide naturally found in human tissues, particularly the thymus gland. It plays a crucial role in tissue repair, wound healing, cell migration, angiogenesis, and immune regulation. More biologically complete than TB-500, it interacts with multiple pathways for superior regenerative effects. Often stacked with BPC-157 for comprehensive healing.

Half-life: ~2 hoursDose: 2–2.5 mg 2x weekly SC

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