Longevity & Telomere Peptides
Peptides that target the molecular drivers of cellular aging — telomere length, senescent cell clearance, and NAD+ metabolism.
3 peptides in this class
Epitalon
→Target: Telomerase activation (pineal-targeted)
Epitalon (Epithalon) is a synthetic tetrapeptide studied for its effects on telomerase activation and potential anti-aging properties. Based on the pineal gland peptide Epithalamin. Researched for longevity, sleep regulation, and cellular health.
FOXO4-DRI
→Target: FOXO4 / p53 interaction (senolytic)
FOXO4-DRI is a D-retro-inverso peptide that selectively eliminates senescent (zombie) cells by disrupting the FOXO4-p53 interaction. This senolytic mechanism triggers apoptosis specifically in damaged cells while sparing healthy ones. A cutting-edge anti-aging research compound based on the landmark 2017 Cell paper.
NAD+
→Target: NAD+ cofactor (sirtuin, PARP, CD38 substrate)
NAD+ (Nicotinamide Adenine Dinucleotide) is a coenzyme essential for cellular energy production, DNA repair, and sirtuin activation. Levels decline significantly with age. Injectable NAD+ provides direct cellular replenishment, bypassing oral bioavailability issues. Research explores applications in anti-aging, neurodegeneration, metabolic health, and addiction recovery.
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