PE-22-28
PE-22-28 is a 7-amino-acid fragment of spadin, a peptide that blocks the TREK-1 potassium channel, studied in mice as a fast-acting antidepressant target. It has no human data. Below: today's vial sizes, prices through our link and the vendor's COA details.
Size
$4.17/mg · In stock
Price
$41.65
List
$49.00
Price shown uses code thepeptidecatalog at Ion Peptide's checkout (15% off list).
Sold by Ion Peptide. The Peptide Catalog does not sell peptides; we earn a commission if you buy through this link, at no extra cost to you. For laboratory research use only, not for human or veterinary use. Not FDA-approved. Nothing on this page is medical or dosing advice.
- Vendor-stated testing: Third-party tested · HPLC + MS · COA per product
- Listed on our pe-22-28 vendor comparison, ordered by our vendor rankings
- Lyophilized powder · laboratory research use only
Research-context information only. PE-22-28 is a research peptide. Protocols, doses, and reactions reported below come from published research and self-reported community sources. This article reports what has been documented, not what should be done. Consult a licensed physician for personal medical decisions.
Vial sizes listed by the vendor
PE-22-28 Vial Sizes & Prices
| Size | List | With our code | Per mg | Availability |
|---|---|---|---|---|
| 10 mg | $49.00 | $41.65 | $4.17 | In stock |
Prices checked today, 5:20 AM CT on Ion Peptide's site, with code thepeptidecatalog applied. Vendor-stated testing: Third-party tested · HPLC + MS · COA per product. The lot certificate is on Ion Peptide's product page. Sizes not re-checked in the last 7 days are hidden. The vendor's checkout is final.
Test results
PE-22-28 Certificate of Analysis
View the PE-22-28 certificate on Ion Peptide's product page.
How to check one: how to verify a peptide COA.
Technical specifications
PE-22-28 chemical & analytical data
- Form
- Lyophilized (freeze-dried) powder in a sealed vial
- Presentation
- 10 mg
- Regulatory status
- Research peptide; research-grade vials are not FDA-approved.
PE-22-28 Reconstitution Calculator
Dilution math and unit conversions. Prefilled using a common vial size for this peptide.
Open calculatorStorage & Handling
Storage at a glance
Proper storage temperatures, shelf life, reconstitution best practices, and travel tips for lyophilized and reconstituted peptides.
Handling specifics
Educational overview on storage, labeling, and traceability considerations for lab environments. Consult primary literature and vendor documentation for specifics.
- Freezer (-20°C): 1+ year
- Refrigerator (2-8°C): 1-3 months
- Room temperature: 2-3 weeks (emergency only)
- MUST refrigerate at 2-8°C
- 4-week maximum shelf life
- NEVER freeze after reconstitution
- Use bacteriostatic water for multi-dose
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PE-22-28 FAQ: Buying, COA, Storage & Research
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PE-22-28 Research Articles
PE-22-28 Dosage: 200-400mcg Community Protocol
The intranasal-vs-SubQ split, why community reports cap at 600mcg, and the exact syringe math for 10mg and 20mg vials of this un-trialed TREK-1 peptide.
buying-guideWhere to Buy PE-22-28: 2026 Vendor Status
One tracked source lists PE-22-28 today; most listings are still gray-market. The real availability picture, alerts, and what compares from verified vendors.
reconstitutionPE-22-28 Reconstitution: 10mg Vial to 5mg/mL
The 2mL BAC water standard, intranasal sprayer prep vs injection draws, and why this 7-amino-acid peptide's storage window runs 3-4 weeks.
benefitsPE-22-28: Antidepressant Effects in 4 Days
A 7-amino-acid spadin fragment with 300x the TREK-1 affinity of its parent — and mouse antidepressant markers in 4 days instead of weeks. The evidence.
Compare PE-22-28 Vendors Before You Buy
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