Thymulin
A thymic peptide for immune regulation and hair regrowth support. Thymulin (also known as Facteur Thymique Sérique or FTS) is a 9-amino acid peptide naturally produced by thymic epithelial cells. It requires zinc for biological activity and plays essential roles in T-cell differentiation, immune regulation, and neuroendocrine function. Research explores applications in immune aging, autoimmune conditions, hair loss, and as an anti-aging intervention. Thymulin levels decline significantly with age.
Compare Prices🧬Key Characteristics
- Type: Thymic Peptide(9 amino acids)
- Cofactor: Zinc Required(Zn-thymulin complex)
- Target: T-lymphocytes(Differentiation)
- Decline: ~90% by age 60(Thymic involution)
Overview
Core Benefits
Key AdvantagesThese are educational summaries of commonly discussed effects in wellness/regenerative contexts, not guarantees.
Thymulin Results Timeline
ProgressionTimeline is illustrative and non-guaranteed. Outcomes vary and are commonly discussed alongside training, nutrition, sleep, and cycling practices.
How It Works
Thymic Peptide — Zinc-Dependent Immune ModulatorTarget → T-Cell Maturation → Immune Reconstitution → Outcomes
T-Cell Precursors + Neuroendocrine Axis
Thymulin is a 9-amino-acid thymic peptide that requires zinc for biological activity. It promotes T-cell differentiation and maturation in the thymus and has neuroendocrine effects on the hypothalamic-pituitary axis. Thymulin levels decline dramatically with age as the thymus involutes.
T-Cell Maturation + Zinc-Dependent Signaling
Thymulin-zinc complex binds to T-cell precursors, promoting their differentiation into mature, functional T-cells. Also modulates cytokine production and has been shown to affect ACTH and beta-endorphin release. The zinc requirement means adequate zinc status is essential for activity.
Immune Reconstitution + Anti-Aging + Hair Growth
Enhanced T-cell function and immune competence. Neuroendocrine modulation may contribute to anti-aging effects. Research also shows potential for hair follicle stimulation — thymulin levels in hair follicles decline with age and may contribute to hair thinning.
Immune Support → Hair Improvements → Vitality
Improved immune function measurable via bloodwork over weeks. Potential hair growth improvements over months. Ensure adequate zinc supplementation for full biological activity. Effects are gradual and cumulative.
What Makes This Peptide Different
Thymulin is unique in its absolute zinc requirement — without zinc, it has no biological activity. This makes zinc supplementation essential when using thymulin. While Thymosin Alpha-1 is the more clinically validated thymic peptide, thymulin's additional research in hair growth and neuroendocrine modulation gives it a unique niche.
Dosing Protocol
Immune Aging / T-cell SupportEducational reference only. Individual responses vary. Consult healthcare provider before use.
Why This Dosing Protocol
Why ensure zinc status first? Thymulin without zinc is biologically inactive. Supplement with zinc (15-30mg/day) before and during thymulin use.
Why 5 on / 2 off? Standard cycling prevents immune over-stimulation while maintaining thymic peptide support.
Diagrams
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Thymulin Pricing
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10 mg / vial
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Reconstitution calculator
Dilution math and unit conversions. Prefilled using a common vial size for this peptide.
Open calculatorEducational Videos
How to Reconstitute Peptides
Handling
Educational overview on storage, labeling, and traceability considerations for lab environments. Consult primary literature and vendor documentation for specifics.
- Freezer (-20°C): 1+ year ✓
- Refrigerator (2-8°C): 1-3 months ✓
- Room temperature: 2-3 weeks (emergency only)
- MUST refrigerate at 2-8°C
- 4-week maximum shelf life
- NEVER freeze after reconstitution
- Use bacteriostatic water for multi-dose
Storage & Handling Guide
Learn proper storage temperatures, shelf life timelines, reconstitution best practices, and travel tips for lyophilized and reconstituted peptides.
FAQ
What is Thymulin?
Thymulin (also called Facteur Thymique Sérique or FTS) is a 9-amino acid peptide produced by thymic epithelial cells. It's unique because it requires zinc to be biologically active. Thymulin plays essential roles in T-cell differentiation, immune regulation, and has connections to neuroendocrine function. Its levels decline significantly with age.
Why does Thymulin require zinc?
Thymulin is only biologically active when bound to zinc — they form a zinc-thymulin complex. Without adequate zinc, thymulin cannot function properly. This is why zinc deficiency impairs immune function, and why thymulin supplementation should be paired with adequate zinc intake. The zinc-thymulin complex is what actually binds to T-cells.
How does Thymulin differ from Thymosin Alpha-1?
Both are thymic peptides but have different structures and mechanisms. Thymulin is 9 amino acids and requires zinc; Thymosin Alpha-1 is 28 amino acids and works independently. Thymulin focuses on T-cell differentiation and has neuroendocrine effects; Tα1 is more broadly immunomodulatory. Tα1 is approved as a drug (Zadaxin) while thymulin remains primarily a research peptide.
What is Thymulin used for?
Research focuses on immune aging (restoring declining thymic function), autoimmune conditions, hair loss (thymulin affects hair follicle cycling), and general immune support. Some anti-aging protocols include thymulin to address age-related immune decline. It's also studied for its neuroendocrine effects on sleep and stress responses.
Why do Thymulin levels decline with age?
The thymus gland shrinks (involutes) with age, dramatically reducing thymulin production. By age 60, thymulin levels may be 90% lower than in youth. This contributes to age-related immune decline (immunosenescence). Restoring thymulin levels is being researched as a way to partially reverse this immune aging.
What are the side effects of Thymulin?
Thymulin is generally well-tolerated as it's a naturally occurring peptide. Possible side effects include injection site reactions and rarely mild immune activation symptoms. Ensure adequate zinc status when using thymulin. Long-term safety data is limited as it's primarily used in research settings.
How long does reconstituted peptide last?
Once mixed with bacteriostatic water, peptides remain stable for up to 4 weeks when refrigerated at 2-8°C (36-46°F). Unopened powder can last 1+ year in the freezer. Get our complete Storage & Travel Guide.
Is this peptide legal to purchase?
Peptides sold "for research purposes only" are legal to purchase in the US, but are not FDA-approved for human use outside of specific medical applications. Always consult a healthcare provider before use.
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Scientific Sources
The following peer-reviewed studies and official resources provide additional scientific context for this peptide:
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