Pancragen

Lyophilized powder

Pancragen is a synthetic tetrapeptide (Lys-Glu-Asp-Trp) from the Khavinson bioregulator series, studied for pancreatic tissue in rats, monkeys and small human studies from one research network. Below: today's vial sizes, prices through our link and the vendor's COA details.

Size

$2.70/mg · In stock

Price

$53.96

List

$59.95

Buy 20 mg at Swiss Chems

Price shown uses code THEPEPTIDECATALOG at Swiss Chems's checkout (10% off list).

Sold by Swiss Chems. The Peptide Catalog does not sell peptides; we earn a commission if you buy through this link, at no extra cost to you. For laboratory research use only, not for human or veterinary use. Not FDA-approved. Nothing on this page is medical or dosing advice.

PancragenSwiss Chems

Research use only

Certificate of AnalysisCertificates from Swiss ChemsView

Listed on our pancragen vendor comparison, ordered by our vendor rankings
Lyophilized powder · laboratory research use only

Research-context information only. Pancragen is a research peptide. Protocols, doses, and reactions reported below come from published research and self-reported community sources. This article reports what has been documented, not what should be done. Consult a licensed physician for personal medical decisions.

Vial sizes listed by the vendor

Pancragen Vial Sizes & Prices

Pancragen vial sizes, prices and lots at Swiss Chems
Size	List	With our code	Per mg	Availability
20 mg	$59.95	$53.96	$2.70	In stock

Prices checked today, 10:06 AM CT on Swiss Chems's site, with code THEPEPTIDECATALOG applied. The lot certificate is on Swiss Chems's product page. Sizes not re-checked in the last 7 days are hidden. The vendor's checkout is final.

Test results

Pancragen Certificate of Analysis

Swiss Chems publishes certificates on its own site. Match the lot number on the vial to its certificate.

View the Pancragen certificate on Swiss Chems's product page.

How to check one: how to verify a peptide COA.

Pancragen Dosing in Clinical Research

Pancreatic Tissue (preclinical / small human studies)

Educational reference only. Individual responses vary. Consult healthcare provider before use.

Vial Size

20 mg

Reconstitution

2 ml BAC water (10 mg/ml)

Dose

2 mg (practitioner-reported); published studies used 10-50 mcg

Timing

AM or PM

Frequency

Once daily

Duration

30 days on, 2 months off, 2-3x/year (practitioner reference)

Protocol Notes

Khavinson KEDW tetrapeptide. Published doses are micrograms: 50 mcg/day IM in old monkeys and 10 mcg/day IM (plus 200 mcg oral) in a small study of older adults with type 2 diabetes. The 2 mg vial figure is a practitioner convention, not a studied dose.

Why This Dosing Protocol

Why the dose gap? Published studies used 10 mcg (older adults) to 50 mcg (monkeys) daily. The 2 mg figure comes from a practitioner reference that applies one protocol to every Khavinson bioregulator, not from Pancragen research.

Full Dosing Guide Reconstitution Calculator Cycle Cost Calculator

How Pancragen Works

Khavinson Peptide Bioregulator — KEDW Tetrapeptide (Preclinical / Small Human Studies)

Target → Signal → Effect → Outcomes

Target

Pancreatic Gene Expression (Proposed)

Pancragen is the tetrapeptide Lys-Glu-Asp-Trp (KEDW), designed from a four-residue fragment shared by insulin-related polypeptides. The developers propose it acts on the preproinsulin gene promoter.

Cellular Signal

Islet-Cell Differentiation Markers (In Vitro)

In aging pancreatic cell cultures, Pancragen raised the differentiation factors Pdx1, Ptf1a, Pax6, Pax4, Foxa2 and Nkx2.2.

Systemic Effect

Glucose and Insulin Response (Animal and Small Human Studies)

In diabetic rats it lowered glucose; in old rhesus monkeys, 50 mcg/day IM for 10 days normalized insulin and C-peptide responses; in small studies of older adults with type 2 diabetes it lowered fasting glucose. All of this comes from one research network.

What You Notice

Not a Felt Effect

The reported changes are laboratory glucose and insulin measures, not sensations. No large or independent trial exists.

What Makes This Peptide Different

Pancragen is the Khavinson bioregulator with the most published dose data — and that data is in micrograms (10-50 mcg), far below the 2 mg course circulated for the 20 mg research vial. Several studies used the amidated form (KEDW-NH2).

Technical specifications

Pancragen chemical & analytical data

Form: Lyophilized (freeze-dried) powder in a sealed vial
Presentation: 20 mg
Regulatory status: Research peptide; research-grade vials are not FDA-approved.

Pancragen Reconstitution Calculator

Dilution math and unit conversions. Prefilled using a common vial size for this peptide.

Open calculator

Storage & Handling

Storage at a glance

Proper storage temperatures, shelf life, reconstitution best practices, and travel tips for lyophilized and reconstituted peptides.

Powder: Freezer

1+ year at -20°C

Reconstituted: Fridge

4 weeks max at 2-8°C

View Complete Storage Guide

Handling specifics

Educational overview on storage, labeling, and traceability considerations for lab environments. Consult primary literature and vendor documentation for specifics.

Powder storage (very stable)

Freezer (-20°C): 1+ year
Refrigerator (2-8°C): 1-3 months
Room temperature: 2-3 weeks (emergency only)

Reconstituted storage (fragile)

MUST refrigerate at 2-8°C
4-week maximum shelf life
NEVER freeze after reconstitution
Use bacteriostatic water for multi-dose

6 answers

Pancragen FAQ: Buying, COA, Storage & Research

What is Pancragen?

Pancragen is the tetrapeptide Lys-Glu-Asp-Trp (KEDW) from the Khavinson bioregulator family, studied for pancreatic function. Research includes diabetic rats, old rhesus monkeys and small studies of older adults with type 2 diabetes, all from the developer's research network.

What doses did Pancragen studies use?

Micrograms. Old rhesus monkeys received 50 mcg per animal per day intramuscularly for 10 days, and a 2019 conference abstract describes older adults receiving 10 mcg intramuscularly daily for 3 weeks plus 200 mcg orally, alongside glibenclamide. The 2 mg course circulated for 20 mg vials is a practitioner convention, not a studied dose.

How strong is the Pancragen evidence?

Better than most bioregulators, but still weak. The human studies are small, short and run by collaborators of the compound's developer, and one is a conference abstract rather than a peer-reviewed paper. There are no large or independent trials.

How long does reconstituted peptide last?

Once mixed with bacteriostatic water, peptides remain stable for up to 4 weeks when refrigerated at 2-8°C (36-46°F). Unopened powder can last 1+ year in the freezer. Get our complete Storage & Travel Guide.

Is this peptide legal to purchase?

Peptides sold "for research purposes only" are legal to purchase in the US, but are not FDA-approved for human use outside of specific medical applications. Always consult a healthcare provider before use.

New to peptides?

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Pancragen Research Articles

dosing

Pancragen Peptide Dosage Chart: 2mg Course vs Studies

Pancragen peptide (KEDW) doses in published studies are micrograms; vendor vials hold 20mg. The reported 2mg course, the study doses, and the vial math.

Compare Pancragen Vendors Before You Buy

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