GHRP-2
A potent growth hormone peptide for muscle growth, fat loss, and recovery. GHRP-2 is a potent synthetic hexapeptide that stimulates growth hormone release through the ghrelin receptor (GHS-R). One of the strongest GHRPs available, it produces significant GH pulses with moderate effects on cortisol, prolactin, and appetite. Often stacked with GHRH peptides like CJC-1295 for synergistic effects.
Compare Prices🧬Key Characteristics
- Length: 6 amino acids(Hexapeptide structure.)
- Half-life: ~15-30 minutes(Short duration requires multiple daily doses.)
- Receptor: GHS-R (ghrelin)(Same pathway as other GHRPs.)
- Potency: High(One of the strongest GHRPs, stronger than Ipamorelin.)
Overview
Core Benefits
Key AdvantagesThese are educational summaries of commonly discussed effects in wellness/regenerative contexts, not guarantees.
GHRP-2 Results Timeline
ProgressionTimeline is illustrative and non-guaranteed. Outcomes vary and are commonly discussed alongside training, nutrition, sleep, and cycling practices.
How It Works
GHRP (Growth Hormone Releasing Peptide) — Potent Ghrelin AgonistReceptor → GH Secretion → Systemic Effects → Outcomes
GHS-R1a (Ghrelin Receptor) — Strong Activation
GHRP-2 activates the same ghrelin receptor as Ipamorelin, but with broader activation. It triggers GH release more potently, but also activates pathways that increase cortisol, prolactin, and appetite — tradeoffs that Ipamorelin avoids through its selective binding.
IP3/DAG + Broader Hormonal Cascade
Ghrelin receptor activation via IP3/DAG pathway produces strong GH pulses. Unlike Ipamorelin, GHRP-2 also activates cortisol and prolactin release pathways, and stimulates moderate appetite increase through central ghrelin signaling. The tradeoff: more potent GH output with more side effects.
Strong GH Spikes → Robust IGF-1 Elevation
The potent GH pulses produce significant IGF-1 elevation, supporting aggressive recovery and body composition changes. The moderate appetite increase can be beneficial for those in caloric surplus (bulking) but unwanted for cutting phases.
Faster Recovery → Body Recomp → Moderate Hunger
Stronger effects than Ipamorelin on recovery and body composition, but with noticeable hunger increase and potential water retention. Sleep improvement is common. Best for those prioritizing maximum GH output who can tolerate the side effects.
What Makes This Peptide Different
GHRP-2 is the middle-ground GHRP — more potent than Ipamorelin but with fewer side effects than GHRP-6. It produces strong GH pulses with moderate cortisol/prolactin elevation and appetite stimulation. Often chosen when maximum GH output is prioritized over selectivity but GHRP-6's extreme hunger effect is unwanted.
GHRP Comparison — Selectivity vs Potency
| Peptide | Half-Life | GH Pattern | What's Unique |
|---|---|---|---|
| Ipamorelin | ~2 hours | Selective GH pulse | Most selective — no cortisol/prolactin/hunger increase |
| GHRP-2 | ~15-30 min | Strong GH pulse | Potent GH + moderate cortisol/prolactin/appetite |
| GHRP-6 | ~15-20 min | Strong GH pulse | Strong GH + significant hunger — ideal for bulking |
| Hexarelin | ~70 min | Strongest GH pulse | Most potent GHRP — but rapid desensitization, short cycles |
Dosing Protocol
Growth HormoneEducational reference only. Individual responses vary. Consult healthcare provider before use.
Popular Stack Protocols
1 stackCommonly paired protocols from the peptide research community. Educational reference only.
🧬 Ipamorelin + GHRP-2
Maximum Growth Hormone ReleaseWhy This Dosing Protocol
Why AM and/or PM? GHRP-2 amplifies existing GH pulses. Twice-daily dosing (morning + bedtime) captures the two main natural GH windows.
Why empty stomach? Insulin blunts GH release. Fast for 2+ hours before injection. The moderate appetite increase from GHRP-2 typically kicks in 20-30 minutes post-injection.
Why stack with GHRH? GHRH peptides like CJC-1295 initiate the pulse while GHRP-2 amplifies it. Together, significantly stronger than either alone.
Diagrams
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GHRP-2 Pricing
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10 mg / vial
In-stock offersOut of stock (1)
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Reconstitution calculator
Dilution math and unit conversions. Prefilled using a common vial size for this peptide.
Open calculatorEducational Videos
How to Reconstitute Peptides
Handling
Educational overview on storage, labeling, and traceability considerations for lab environments. Consult primary literature and vendor documentation for specifics.
- Freezer (-20°C): 1+ year ✓
- Refrigerator (2-8°C): 1-3 months ✓
- Room temperature: 2-3 weeks (emergency only)
- MUST refrigerate at 2-8°C
- 4-week maximum shelf life
- NEVER freeze after reconstitution
- Use bacteriostatic water for multi-dose
Storage & Handling Guide
Learn proper storage temperatures, shelf life timelines, reconstitution best practices, and travel tips for lyophilized and reconstituted peptides.
FAQ
How does GHRP-2 compare to Ipamorelin?
GHRP-2 is more potent than Ipamorelin, producing stronger GH release. However, it's less selective — it increases cortisol and prolactin levels more, and causes moderate appetite increase. Choose GHRP-2 for maximum GH output; choose Ipamorelin for fewer side effects.
What are the main side effects of GHRP-2?
Common side effects include moderate hunger increase, water retention, tingling/numbness in extremities, and potential cortisol/prolactin elevation. Some users report vivid dreams. These effects are generally dose-dependent and more pronounced than with Ipamorelin.
Should GHRP-2 be stacked with other peptides?
Yes, GHRP-2 is commonly stacked with GHRH peptides like CJC-1295 for synergistic effects. The GHRH peptide increases the number of pituitary cells releasing GH, while GHRP-2 increases output per cell. This combination produces stronger results than either peptide alone.
What is the typical dosing frequency for GHRP-2?
Common research dosages range from 100-300 mcg per injection, typically administered 2-3 times daily before meals and/or at bedtime on a 5 days on, 2 days off schedule (8 weeks on, 8 weeks off). The bedtime dose takes advantage of natural GH release during sleep. Best taken on an empty stomach.
How long does reconstituted peptide last?
Once mixed with bacteriostatic water, peptides remain stable for up to 4 weeks when refrigerated at 2-8°C (36-46°F). Unopened powder can last 1+ year in the freezer. Get our complete Storage & Travel Guide.
Is this peptide legal to purchase?
Peptides sold "for research purposes only" are legal to purchase in the US, but are not FDA-approved for human use outside of specific medical applications. Always consult a healthcare provider before use.
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Scientific Sources
The following peer-reviewed studies and official resources provide additional scientific context for this peptide:
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