AOD-9604
A fat loss peptide that targets stubborn fat without affecting blood sugar or growth. AOD-9604 is a modified fragment of human growth hormone (HGH fragment 176-191) studied for fat metabolism and weight loss. It mimics GH's lipolytic effects without affecting blood sugar or growth. Previously in clinical trials for obesity; now popular in research settings.
Compare Prices🧬Key Characteristics
- Length: 16 amino acids(C-terminal fragment of HGH.)
- Origin: HGH 176-191(Modified growth hormone fragment.)
- Mechanism: Lipolysis(Fat burning without growth effects.)
- Primary Use: Fat loss(Targets stubborn fat areas.)
Overview
Core Benefits
Key AdvantagesThese are educational summaries of commonly discussed effects in wellness/regenerative contexts, not guarantees.
AOD-9604 Results Timeline
ProgressionTimeline is illustrative and non-guaranteed. Outcomes vary and are commonly discussed alongside training, nutrition, sleep, and cycling practices.
How It Works
Fat Loss Peptide — HGH FragmentTarget → Lipolytic Signal → Fat Metabolism → Outcomes
Beta-3 Adrenergic Receptors on Adipose Tissue
AOD-9604 is a modified fragment of human growth hormone (amino acids 176-191). It retains GH's fat-mobilizing properties while lacking the growth-promoting and blood-sugar-affecting actions. It directly targets fat cells without affecting IGF-1 or insulin levels.
Lipolysis Activation Without IGF-1 Elevation
Stimulates lipolysis (fat breakdown) in adipose tissue through a mechanism similar to natural GH, but without triggering IGF-1 production or affecting glucose metabolism. This selective action is why AOD-9604 is considered a "fat-only" GH fragment.
Targeted Fat Mobilization → No Anabolic Effects
Fat mobilization and oxidation without the muscle-building, growth, or blood sugar effects of full GH. Does not cause insulin resistance or affect blood sugar — making it suitable for those who want fat loss without the broader hormonal effects of GH peptides.
Gradual Fat Loss → No Other Hormonal Effects
Gradual fat reduction over weeks to months, particularly effective when combined with fasted training. No changes in muscle mass, sleep, or other GH-related effects — this is purely a fat-loss peptide. Effects are more subtle than full GH peptides.
What Makes This Peptide Different
AOD-9604 is unique as a fat-only GH fragment. Unlike full GH peptides (CJC-1295, Ipamorelin) that affect sleep, muscle, recovery AND fat, AOD-9604 isolates just the lipolytic effect. It doesn't raise IGF-1, doesn't affect blood sugar, and doesn't build muscle. This makes it ideal for those who specifically want fat loss without broader hormonal changes.
Dosing Protocol
Fat LossEducational reference only. Individual responses vary. Consult healthcare provider before use.
Why This Dosing Protocol
Why fasted, in the morning? AOD-9604 stimulates lipolysis. Taking it fasted in the morning maximizes fat oxidation — insulin is already low from overnight fasting, and morning activity further drives fat utilization.
Why it doesn't affect blood sugar: Unlike full GH (which causes insulin resistance), AOD-9604 lacks the amino acid sequences responsible for glucose effects. This is by design — it's specifically the fat-loss fragment.
Diagrams
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AOD-9604 Pricing
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5 mg / vial
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Reconstitution calculator
Dilution math and unit conversions. Prefilled using a common vial size for this peptide.
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How to Reconstitute Peptides
Handling
Educational overview on storage, labeling, and traceability considerations for lab environments. Consult primary literature and vendor documentation for specifics.
- Freezer (-20°C): 1+ year ✓
- Refrigerator (2-8°C): 1-3 months ✓
- Room temperature: 2-3 weeks (emergency only)
- MUST refrigerate at 2-8°C
- 4-week maximum shelf life
- NEVER freeze after reconstitution
- Use bacteriostatic water for multi-dose
Storage & Handling Guide
Learn proper storage temperatures, shelf life timelines, reconstitution best practices, and travel tips for lyophilized and reconstituted peptides.
FAQ
What is AOD-9604?
AOD-9604 is a modified fragment of human growth hormone (specifically the C-terminus, amino acids 176-191). It was developed to isolate GH's fat-burning properties without effects on blood sugar or growth. It mimics GH's lipolytic (fat-burning) mechanism.
Is AOD-9604 FDA approved?
AOD-9604 is not FDA-approved for weight loss. It went through clinical trials for obesity but didn't achieve approval. However, it remains popular in research settings and is available in some countries for specific uses.
How does AOD-9604 burn fat?
AOD-9604 stimulates lipolysis (fat breakdown) and inhibits lipogenesis (fat formation) by mimicking the fat-burning portion of growth hormone. It activates beta-3 adrenergic receptors in fat tissue, triggering the release of stored fatty acids for energy. Unlike full GH, it doesn't affect blood sugar or promote cell growth.
Does AOD-9604 affect blood sugar like growth hormone?
No, this is AOD-9604's key advantage. Full growth hormone can cause insulin resistance and elevated blood sugar, but AOD-9604 was specifically designed to isolate the fat-burning effects without the metabolic side effects. Studies show it doesn't affect glucose tolerance or insulin sensitivity.
What is the typical AOD-9604 dosage?
A common research dosage is 300 mcg per day, administered in the morning on an empty stomach to maximize fat oxidation (5 days on, 2 days off). Cycles typically run 8 weeks on, 8 weeks off. AOD-9604 does not affect blood sugar or IGF-1 levels, which is its key advantage over full growth hormone.
Can AOD-9604 be combined with other peptides?
Yes, AOD-9604 is often stacked with other fat loss or GH-related peptides. Common combinations include CJC-1295/Ipamorelin for GH benefits plus targeted fat loss, or with Tesamorelin for enhanced visceral fat reduction. Some combine it with Frag 176-191, though they have similar mechanisms.
What are the side effects of AOD-9604?
AOD-9604 is generally well-tolerated with minimal side effects. Some users report injection site reactions (redness, slight swelling), headache, or mild flu-like symptoms initially. Unlike full GH, it doesn't cause water retention, joint pain, or blood sugar issues. Long-term safety data is limited.
How long does it take to see results with AOD-9604?
Most users report noticeable fat loss effects within 4-8 weeks of consistent use. Results vary based on diet, exercise, and individual metabolism. It works best when combined with a caloric deficit and regular exercise. Don't expect dramatic overnight changes — it enhances fat metabolism rather than causing rapid weight loss.
How long does reconstituted peptide last?
Once mixed with bacteriostatic water, peptides remain stable for up to 4 weeks when refrigerated at 2-8°C (36-46°F). Unopened powder can last 1+ year in the freezer. Get our complete Storage & Travel Guide.
Is this peptide legal to purchase?
Peptides sold "for research purposes only" are legal to purchase in the US, but are not FDA-approved for human use outside of specific medical applications. Always consult a healthcare provider before use.
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Scientific Sources
The following peer-reviewed studies and official resources provide additional scientific context for this peptide:
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