Weight Loss & Metabolic Peptides

Ribupatide: 19.2% Weight Loss and No Way to Buy It

Kailera's ribupatide (KAI-9531) hit 19.2% weight loss in China's Phase 3 and is now in global trials. Why it isn't for sale — and what ships today.

Lilly Sues 6 Retatrutide Sellers: Who's Affected

Eli Lilly filed six suits on August 12 over retatrutide sales. The named defendants, the payment-processor ask, and what actually changes for buyers.

Once-Yearly Semaglutide Implant: Phase 1 Dosing Done

Vivani dosed all 20 subjects in SLIM-1, the first human trial of a once-yearly semaglutide implant. Novo is evaluating it. What buyers can use now.

GLP-1 Antitrust Suit Tossed: What Changes for Buyers

A Texas judge dismissed Strive's antitrust case against Lilly and Novo, ruling compounded GLP-1s never competed with the branded drugs at all.

Peptide Vendor Code Names Decoded: GLP-3, MHC-3 RT & More

GLP-3 RT, ION-3R, EZP-3P and R-30 are the same compound. A decoder for every obfuscated vendor SKU, and what each one actually costs per mg.

Compounded GLP-1 State Laws: Who Restricts What

California codified a stricter copy rule, Ohio suspended 30+ licenses, Washington issued stop-service orders. The state layer now gates compounded GLP-1s.

Where to Buy Retatrutide: Price & Vendor Guide

One vendor sells 60mg vials at half the per-mg cost of 12mg — but COA matters more than price. Vial sizes, cost per week, and vendor scores.

Retatrutide Cycle Protocol: Length, Taper, Off-Cycle

Community sources cluster around 8-on / 8-off. Covers cycle length, week-by-week titration, tapering, off-cycle reports, and restart protocols.

SLU-PP-332 Reconstitution: Vial Mixing & Oral Cap Notes

Ion's 30 mg vial is the only injectable path. Oral caps need no mixing — but the published bioavailability question changes the math entirely.

SLU-PP-332 Dosage Chart: 500 mcg–1.5 mg Daily SC

Community SubQ protocols run 500–1,500 mcg/day, derived from mouse-to-human dose scaling. Why oral capsules likely fail and how the math gets there.

Buy SLU-PP-332: Compare 2 Vendors, From $49.99

Compare 2 SLU-PP-332 vendors side by side: from $49.99 a vial, best value $1.97/mg. Codes save up to 10%. Vial sizes, COA status, real cost per week.

RetaCagri Reconstitution: Pre-Mixed & Separate Vial Math

12.5/2.5 and 20/4 pre-mix vials in 2 mL BAC water, plus the separate-vial titration math. Insulin syringe units for every common community dose.

What Doctors Think About Peptides: New Survey Data

48% of physicians say patients disclosed peptide use last year — and 84% got their information from influencers, not doctors. The full survey data.

What Is Bioglutide (NA-931)? Oral GLP-4 Agonist

Bioglutide (NA-931): the oral quadruple agonist adding IGF-1 to retatrutide's targets. What the ADA 2025 trial data reported, and the accessible analog.

Bioglutide (NA-931) Phase 2: 13.8% Oral Weight Loss

The Phase 2 trial reported oral quadruple agonist NA-931 hit 13.8% weight loss with no muscle loss. How it stacks up to retatrutide.

Quintuple Agonist Beats Retatrutide in Rats: VRX-0075

A 5-receptor obesity peptide, VRX-0075, beat retatrutide for weight loss in obese rats at ADA 2026. What the data means and what you can buy now.

Enicepatide: Roche's CT-388 Hits 22.5% at ADA 2026

Roche's enicepatide (CT-388) hit 22.5% placebo-adjusted weight loss at ADA 2026. What the dual GLP-1/GIP data means for buyers right now.

Petrelintide: 10.7% Weight Loss, Placebo-Like GI

Roche's amylin drug petrelintide hit 10.7% weight loss at ADA 2026 with placebo-like GI tolerability. What the ZUPREME-1 data means for buyers.

Where to Buy Bioglutide (NA-931): 2026 Status

Bioglutide (NA-931) isn't for sale yet — it's still in trials. See the real 2026 availability, why current listings aren't legit, and get launch alerts.

Buy L-Carnitine: Compare 2 Vendors, From $40

Compare 2 L-Carnitine vendors side by side: from $40 a vial, best value $0.01/mg. Codes save up to 15%. Vial sizes, COA status, real cost per week.

Buy Vitamin B12: Price, COA & Cost Per Week

Only 1 vetted Vitamin B12 source right now: $35 a vial, $3.50/mg. Codes save up to 15%. COA status and real cost per week.

Buy Survodutide: Price, COA & Cost Per Week

Only 1 vetted Survodutide source right now: $78 a vial, $7.80/mg. Codes save up to 10%. COA status and real cost per week.

Buy Cagrilintide: Compare 4 Vendors, From $44

Compare 4 Cagrilintide vendors side by side: from $44 a vial, best value $8.80/mg. Codes save up to 50%. Vial sizes, COA status, real cost per week.

Peptide Stacks Under $200/Month

4 complete peptide protocols under $200/month — fat loss, healing, anti-aging, sleep. Per-peptide cost math, vendor picks, and which vial to buy.

GLP-4 vs GLP-5: Bioglutide vs VRX-0075

Bioglutide (GLP-4) adds muscle-sparing IGF-1 and has oral human data; VRX-0075 (GLP-5) adds amylin for deeper loss but is rat-only. Full comparison.

Bioglutide vs Retatrutide: Oral Quad vs Injectable

Bioglutide (NA-931) is an oral quadruple agonist; retatrutide an injectable triple. How the two obesity compounds actually compare in 2026.

SLU-PP-332 vs MOTS-c: Two Exercise Mimetics

Synthetic ERR pan-agonist vs mitochondria-encoded AMPK activator. Same goal, opposite philosophies, and the stack rationale that ties them.

Cagri+Tirz vs Cagri+Sema: Amylin Pairing Choice

REDEFINE 1 hit 22.7% with cagrilintide + semaglutide. Cagrilintide + tirzepatide has stronger GIP. Mechanistic case, trial data, and the open question.

Oral GLP-1 vs Injectable: Pills vs Shots Compared

Orforglipron and Pfizer's PF-3944 are reshaping the GLP-1 landscape — when oral pills make sense, when shots still win, and what trials show.

Semaglutide vs Tirzepatide: One Clear Winner

Tirzepatide hits two receptors, semaglutide hits one — but that's not the whole story. Head-to-head on weight loss, sides, and cost.

Bioglutide (NA-931) Trial Results Timeline

Bioglutide (NA-931) trials reported up to 13.8% weight loss by week 13. How the oral quadruple agonist's results built across Phase 1 and Phase 2.

L-Carnitine Results Timeline: What to Expect

L-carnitine works on muscle stores, not blood levels — which is why recovery and fatigue effects take weeks, not days. Here's the documented timeline.

Vitamin B12 Results: Deficiency Timeline

Energy can shift in days, blood counts take weeks, nerves take months — and if you're not deficient, B12 does nothing. The honest timeline.

Tesofensine Results: Week-by-Week Timeline

Appetite suppression in days, weight loss over months. What the Phase 2 trial documented week 1 through month 6 at 0.5mg/day oral.

Survodutide Results: Week-by-Week Timeline

Appetite drops in week 1, but the 18.7% weight-loss figure took 46 weeks of titration. Full trial-reported timeline by phase and use case.

Liraglutide Results: Week-by-Week Timeline

Appetite shifts in week 1, but trial weight loss took 56 weeks. The full daily-injection timeline by phase, grounded in the SCALE trial data.

Bioglutide (NA-931) Dosage: What Trials Used

Bioglutide (NA-931) is oral, not injected. See the exact dose the Phase 2 trial used for 13.8% weight loss — and why no research-use protocol exists yet.

L-Carnitine Dosage: 500-2000 mg Protocols

Why oral L-carnitine is only ~15% absorbed, how injectable 500 mg/mL forms bypass that, and the 500-2000 mg/day ranges used across the clinical literature.

Vitamin B12 Dosage: 1000 mcg IM & Oral Protocols

The established deficiency dose is 1000 mcg. See why high-dose oral B12 matches injections, plus loading-vs-maintenance schedules and form differences.

Bioglutide (NA-931) Benefits: Oral, No Muscle Loss

Bioglutide (NA-931) is oral, once-daily. Phase 2 subjects on 150mg/day averaged 13.8% weight loss with no muscle loss reported. What the trial data shows.

L-Carnitine Benefits: Faster Recovery, Less Fatigue

The strongest L-carnitine evidence is exercise recovery and fatigue — not fat burning. See what trials actually show, including the modest weight effect.

Vitamin B12 for Nerve & Blood Health

The energy boost everyone cites is B12's weakest-evidenced benefit. What clinical trials actually show — anemia, nerves, homocysteine, cognition.

SLU-PP-332: Mice Lost 12% Body Weight in 30 Days

DIO mice on SLU-PP-332 ran 70% longer and gained 10x less fat than controls. What ERR pan-agonism does, plus the asterisks behind the data.

Retatrutide + Cagrilintide Benefits: 4 Pathways

GLP-1, GIP, glucagon, plus amylin — four metabolic axes in one stack. What the per-component trial data implies about combined effect.

Tirzepatide: 22.5% Weight Loss + Liver Fat

Weight loss gets the headlines, but tirzepatide's liver fat data may matter more. 8 research-backed effects with cited studies.

L-Carnitine Side Effects: What's Real

L-carnitine is well tolerated — but GI upset, a fishy body odor, and a debated TMAO–heart-risk signal are worth understanding before you buy.

Vitamin B12 Side Effects: What's Real

Vitamin B12 is one of the safest supplements there is — but injection reactions, acne flares, and a scary-sounding cancer signal are worth understanding.

5-Amino-1MQ Side Effects: What Research Shows

Animal models report clean safety. Community data adds mild GI and transient fatigue. Full breakdown of investigational dataset.

SLU-PP-332 Side Effects: Zero Human Data, Mouse Signals

No human Phase 1, no incidence rates. What the mouse studies and ERR receptor expression actually predict — cardiac, hepatic, and the unknown long tail.

RetaCagri Side Effects: Combined GI Burden + Dysesthesia

Both compounds slow gastric emptying via different pathways — combined nausea is the rate-limiter. Plus retatrutide's dysesthesia signal ≥9mg.

Tirzepatide Side Effects: 29% Nausea, When It Stops

29% of users get nausea at max dose — most resolves by week 4. Full safety breakdown: GI side effects, gastroparesis, thyroid flags, when to stop.

Retatrutide vs Semaglutide: Triple vs Single Agonist

Phase 2 trials reported 24.2% weight loss for retatrutide vs 14.9% for semaglutide in STEP 1 — but only one is FDA-approved. Full side-by-side.

Liraglutide vs Semaglutide: 2.5x Weight Loss Gap

STEP 8 head-to-head: 15.8% vs 6.4% weight loss. Side-by-side dosing, side effects, and cost — and which one to actually pick.

Cagrilintide vs Semaglutide: Different Paths

They target different receptors entirely — and combining them produces 22.7% weight loss. Mechanism, efficacy, and when to use each.

SLU-PP-332 + Retatrutide Stack: Eat Less, Burn More

Triple-agonist appetite suppression + ERR pan-agonist mitochondrial output. Why community references frame it as the cleanest mechanistic pair.

SLU-PP-332 Bloodwork: 7 Labs Researchers Track

Lactate may be the marker that tells you if ERR pan-agonism is doing anything. Cardiac, metabolic, and liver labs published preclinical work tracked.

Tirzepatide Bloodwork: 7 Labs to Track

Most skip calcitonin — the one marker that catches the rarest but most serious risk. 7 essential labs with optimal ranges and testing schedule.

Survodutide Bloodwork: 8 Labs to Track

Liver enzymes are the one most skip — and shouldn't with a glucagon agonist. 8 essential labs with optimal ranges and testing schedule.

5-Amino-1MQ Bloodwork: 8 Labs to Track

Most skip the insulin marker that shows if 5-amino-1MQ is working. 8 essential labs with optimal ranges, testing schedule, and what results mean.

$30 vs $300 Semaglutide: Where the Money Goes

Same Chinese factories, 10x price gap. We break down every dollar of compounded GLP-1 markup — what's real safety value vs telehealth marketing.

Retatrutide vs Tirzepatide: What the Trials Show

Retatrutide hit 24% weight loss vs tirzepatide's 22.5% — but it also raises heart rate more, and the glucagon receptor is why. What the data shows.